N TSITIZIN HOSILALARINING ANTIDOT XUSUSIYATLARI
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Tsitizin, N-tsitizin hosilalari, antidot, nikotinik retseptorlar, zaharlanish, organofosfatlar, farmakologiya, nikotin antagonizmi.Abstrak
Ushbu ilmiy tezisda o‘simlik alkaloidi bo‘lgan N-tsitizin (cytisine) va uning hosilalarining antidot xususiyatlari zamonaviy ilmiy manbalar asosida tahlil qilinadi. Tsitizin — bu nikotinik atsetilxolin retseptorlarining qisman agonisti bo‘lib, asosan tamaki qaramligini davolashda qo‘llanadi. So‘nggi yillarda uning farmakologik profili, toksik moddalarga qarshi himoya potensiali, xususan nikotin zaharlanishi, organofosfat birikmalar ta’siri va markaziy nerv tizimi toksikliklarida qo‘llash imkoniyatlari o‘rganilmoqda. Maqolada tsitizin hosilalarining molekulyar mexanizmlari, farmakodinamikasi va eksperimental natijalari umumlashtiriladi.
Iqtiboslar
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