PHARMACOTHERAPY: CLINICAL-PHARMACOLOGICAL APPROACHES TO METABOLISM-ACTIVATING AND METABOLISM-CORRECTING DRUGS

Abstrak

Metabolism-activating and metabolism-correcting drugs are extensively employed in contemporary pharmacotherapy. This article examines their clinical-pharmacological properties, therapeutic applications, and influence on pharmacokinetic and pharmacodynamic factors, as well as their role in individualized treatment strategies, including during pregnancy. The review highlights the clinical significance of these agents within the context of metabolic disturbances, drug–drug interactions (including metabolites and vitamins), and strategies for optimizing therapeutic efficacy.