MULTIMODAL APPROACH TO RADIOLOGIC DIAGNOSTICS OF OSTEOGENIC SARCOMA IN CHILDREN
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https://doi.org/10.5281/zenodo.16760284;
Osteogenic Sarcoma, Pediatric Oncology, Radiologic Diagnostics, MRI, CT, PET, Multimodal Imaging, Children.Abstrak
Osteogenic sarcoma is one of the most common malignant bone tumors in pediatric patients, necessitating early and accurate diagnosis to improve treatment outcomes. A multimodal radiological approach, integrating conventional radiography, MRI, CT, and PET scans, offers a comprehensive diagnostic pathway. This study explores the diagnostic yield and clinical impact of these modalities based on a retrospective analysis of pediatric cases. Findings reveal that MRI and PET provide superior sensitivity for local and metastatic assessment, while X-rays remain critical for initial detection. By employing combined imaging strategies, clinicians can optimize diagnostic accuracy and therapeutic planning. This paper underscores the critical role of comprehensive radiological evaluation in managing osteogenic sarcoma in children.
Iqtiboslar
Ottaviani, G., & Jaffe, N. (2009). The epidemiology of osteosarcoma. Cancer Treatment and Research, 152, 3-13.
Bielack, S. S., et al. (2002). Prognostic factors in high-grade osteosarcoma of the extremities or trunk: An analysis of 1,702 patients. Journal of Clinical Oncology, 20(3), 776-790.
Costelloe, C. M., et al. (2009). Imaging in osteosarcoma. Journal of Clinical Oncology, 27(32), 5326-5331.
Kaste, S. C. (2008). Imaging pediatric bone sarcomas. Radiologic Clinics, 46(3), 455-471.
Iyer, R., et al. (2013). The diagnostic and prognostic value of MRI in osteosarcoma. Pediatric Radiology, 43(10), 1237–1245.
Huang, J., et al. (2012). Role of PET/CT in the staging and evaluation of treatment response in pediatric sarcomas. Pediatric Radiology, 42(10), 1180-1189.
Eary, J. F., et al. (2011). Quantitative FDG PET in sarcoma patients: Metabolic response as a prognostic indicator. Radiology, 261(2), 511-520.
Franzius, C., & Schober, O. (2006). Role of PET and PET/CT in the diagnosis and management of bone sarcomas. Eur J Nucl Med Mol Imaging, 33(10), 1125-1132.
Weiss, J., et al. (2021). Advancements in multimodal imaging for pediatric oncology. Pediatric Blood & Cancer, 68(7), e28934..
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