CLINICAL AND FUNCTIONAL FACTORS OF ACUTE ISCHEMIC STROKE DEVELOPMENT IN ACUTE MYOCARDIAL INFARCTION
Keywords:
Acute myocardial infarction, acute ischemic stroke, cerebrovascular complications, atrial fibrillation, arterial hypertension, thromboembolism, hemodynamic disorders, left ventricular ejection fraction, risk factors, early diagnosis.Abstract
Acute myocardial infarction and acute ischemic stroke remain leading causes of mortality and disability worldwide. The development of ischemic stroke during acute myocardial infarction significantly worsens the prognosis and increases the risk of severe complications. This study investigated the clinical and functional factors associated with the development of acute ischemic stroke in patients with acute myocardial infarction. Central hemodynamic parameters, cardiac rhythm disturbances, myocardial contractile function, concomitant diseases, and metabolic disorders were analyzed. The study identified arterial hypertension, atrial fibrillation, chronic heart failure, diabetes mellitus, hyperlipidemia, and reduced left ventricular ejection fraction as the major risk factors. The combination of cardiac and vascular disorders contributes to thromboembolic complications and early ischemic stroke after myocardial infarction. Early identification of risk factors, timely cardiological and neurological monitoring, and a comprehensive treatment approach can improve therapeutic outcomes and patient prognosis.
References
Adams HP, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. Stroke. 1993;24(1):35–41. doi:10.1161/01.STR.24.1.35
O’Gara PT, Kushner FG, Ascheim DD, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction. Circulation. 2013;127(4):e362–e425. doi:10.1161/CIR.0b013e3182742cf6
Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the early management of patients with acute ischemic stroke. Stroke. 2018;49(3):e46–e110. doi:10.1161/STR.0000000000000158
Ibanez B, James S, Agewall S, et al. 2017 ESC Guidelines for the management of acute myocardial infarction. Eur Heart J. 2018;39(2):119–177. doi:10.1093/eurheartj/ehx393
Yaghi S, Bernstein RA, Passman R, et al. Cryptogenic stroke: research and practice. Circ Res. 2017;120(3):527–540. doi:10.1161/CIRCRESAHA.116.308447
Hart RG, Diener HC, Coutts SB, et al. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol. 2014;13(4):429–438. doi:10.1016/S1474-4422(13)70310-7
January CT, Wann LS, Calkins H, et al. 2019 AHA/ACC/HRS focused update on atrial fibrillation. Circulation. 2019;140(2):e125–e151. doi:10.1161/CIR.0000000000000665
Goldstein LB, Bushnell CD, Adams RJ, et al. Guidelines for the primary prevention of stroke. Stroke. 2011;42(2):517–584. doi:10.1161/STR.0b013e3181fcb238
Jauch EC, Saver JL, Adams HP, et al. Guidelines for the early management of acute ischemic stroke. Stroke. 2013;44(3):870–947. doi:10.1161/STR.0b013e318284056a
Levine GN, Bates ER, Bittl JA, et al. 2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy. Circulation. 2016;134(10):e123–e155. doi:10.1161/CIR.0000000000000404
Koudstaal PJ, et al. Stroke and myocardial infarction: shared mechanisms and risk factors. Lancet. 2000;355:180–185.
Windecker S, Kolh P, Alfonso F, et al. 2014 ESC/EACTS guidelines on myocardial revascularization. Eur Heart J. 2014;35(37):2541–2619. doi:10.1093/eurheartj/ehu278
Downloads
Published
Issue
Section
How to Cite
