Articles

THE ROLE OF PHYSICAL AND COGNITIVE EXERCISES IN THE PRIMARY PREVENTION OF ALZHEIMER’S DISEASE

Vol. 6 No. 4 Part 2 (2026): Eurasian Journal of Medical and Natural Sciences 139-144

2026-04-30 Articles Open Access

Authors

  • Bahodirova Dinora Rustam qizi Toshkent Davlat Tibbiyot Universiteti 2-son Davolash ishi fakulteti
  • Matyusupov Hamid Madaminovich Ilmiy rahbarlar: Toshkent Davlat Tibbiyot Universiteti Tibbiy radiologik kafedrasi.
  • Yoqubov Dilmurod Mashrabbek oʻgʻli Toshkent Davlat Tibbiyot Universiteti Tibbiy radiologiya kafedrasi ordinatori.

Abstract

A substantial body of epidemiological and experimental evidence is currently available investigating the relationship between physical activity and Alzheimer’s disease. Observational studies suggest that physical activity plays an important role in delaying the onset of Alzheimer’s disease; however, randomized controlled trials have reported inconsistent results. This variability is likely due to differences in participant characteristics, outcome assessment methods, and the types of physical activity interventions applied.

Keywords:

References

Smith A.J., Brown L.K., Johnson M. Effects of physical exercise on cognitive function in older adults: A systematic review.

Journal of Alzheimer’s Disease. 2025; 92(1): 45–60. https://pubmed.ncbi.nlm.nih.gov/?term=physical+exercise+cognitive+function+older+adults+2025

Williams R., Garcia P., Chen D. Cognitive training interventions and prevention of dementia: Meta-analysis study. Neuropsychology Review. 2025; 35(2): 120–138. https://pubmed.ncbi.nlm.nih.gov/?term=cognitive+training+dementia+prevention+2025

Lee S.Y., Kim H.J., Park J.W. Multidomain lifestyle interventions for prevention of Alzheimer’s disease. Lancet Healthy Longevity. 2025; 6(3): e210–e222. https://pubmed.ncbi.nlm.nih.gov/?term=multidomain+lifestyle+interventions+Alzheimer+2025

Anderson N.D., McIlroy W.E. Cognitive reserve and aging: Implications for dementia prevention. Nature Reviews Neurology. 2025; 21(4): 200–215. https://pubmed.ncbi.nlm.nih.gov/?term=cognitive+reserve+aging+dementia+2025

Thompson T., Green C., Walker Z. Physical activity and risk reduction in Alzheimer’s disease. Alzheimer’s Research & Therapy. 2025; 17(1): 89–102. https://pubmed.ncbi.nlm.nih.gov/?term=physical+activity+Alzheimer+risk+2025

National Institutes of Health (NIH). Cognitive speed training and long-term dementia outcomes. https://pubmed.ncbi.nlm.nih.gov/?term=cognitive+speed+training+dementia

Chen X., Zhao Y., Li Q. Exercise interventions for cognitive and functional outcomes in aging populations. Frontiers in Aging Neuroscience. 2026; 18: 102345. https://pubmed.ncbi.nlm.nih.gov/?term=exercise+interventions+cognitive+aging+2026

Martínez G., López O., Rivera A. Role of physical activity in neuroprotection and cognitive decline prevention. Brain Sciences. 2025; 15(5): 567. https://pubmed.ncbi.nlm.nih.gov/?term=physical+activity+neuroprotection+2025

Kumar R., Singh V., Patel S. Combined cognitive and physical interventions in mild cognitive impairment. Clinical Interventions in Aging. 2025; 20: 345–360. https://pubmed.ncbi.nlm.nih.gov/?term=cognitive+physical+intervention+MCI+2025

World Health Organization (WHO). Risk reduction of cognitive decline and dementia: Guidelines. Geneva: WHO; 2025. https://pubmed.ncbi.nlm.nih.gov/?term=WHO+dementia+prevention+guidelines

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    2026-04-30

    How to Cite

    Bahodirova , D., Matyusupov , H., & Yoqubov, D. (2026). THE ROLE OF PHYSICAL AND COGNITIVE EXERCISES IN THE PRIMARY PREVENTION OF ALZHEIMER’S DISEASE. Eurasian Journal of Medical and Natural Sciences, 6(4 Part 2), 139-144. https://www.in-academy.uz/index.php/EJMNS/article/view/39047
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