Articles

DEVELOPMENT OF TRICARDION CAPSULE TECHNOLOGY BASED ON LEONURUS TURCESTANICUS, MENTHA × PIPERITA, AND CRATAEGUS SANGUINEA PALL.: A REVIEW OF PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES

Vol. 5 No. 5 (2025): Eurasian Journal of Medical and Natural Sciences 13-16

2025-05-06 Articles CC BY 4.0 Open Access

Authors

  • Nodira Bakhramova Tashkent Pharmaceutical Institute
  • Firuza Maksudova Tashkent Pharmaceutical Institute

Abstract

The Tricardion capsule is a phytotherapeutic formulation developed using extracts of three medicinal plants: Leonurus turcestanicus, Mentha × piperita (commonly referred to as peppermint), and Crataegus sanguinea Pall. (hawthorn). These plants are native to Central Asia and are widely found in various regions of Uzbekistan. Each species has a long-standing history in traditional medicine and is known for its cardiovascular, anti-inflammatory, and antispasmodic properties. This review aims to summarize the botanical characteristics, phytochemical compositions, and pharmacological effects of the three plants. The potential synergistic benefits of combining these botanical ingredients into a single capsule are also discussed. Emphasis is placed on their cardiovascular applications, which form the basis for the development of the Tricardion capsule. The article draws from regional and international scientific literature, including studies conducted by Uzbek researchers. The findings support the scientific rationale for using these plants in combination for the prevention and management of cardiovascular conditions.

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References

WHO Monographs on Selected Medicinal Plants, Volumes 1–4.

Toshov, P., & Pulatova, T. (2021). Cardioprotective properties of Central Asian medicinal plants: A review. Journal of Herbal Pharmacology, 15(3), 45–52.

Morozova, T. (2019). Development of phytotherapeutic agents based on regional flora (Doctoral dissertation). Tashkent Pharmaceutical Institute.

Bekbolatova, E. N., Sakipova, Z. B., Ibragimova, L. N., Keleke, A. S., Iklasova, A. Sh., Turdieva, K. A., & Zhumagaliev, A. N. (2020). Phytochemical study of Crataegus species growing in Central Asia. Pharmaceutical Sciences and Research, 18(2), 112–120.

Davlatova, M. S., & Amonov, M. K. U. (2022). Comparative analysis of Mentha piperita extracts in cardiovascular applications. Uzbek Journal of Natural Products, 9(4), 77–84.

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    Published

    2025-05-06

    How to Cite

    Bakhramova , N., & Maksudova , F. . (2025). DEVELOPMENT OF TRICARDION CAPSULE TECHNOLOGY BASED ON LEONURUS TURCESTANICUS, MENTHA × PIPERITA, AND CRATAEGUS SANGUINEA PALL.: A REVIEW OF PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES. Eurasian Journal of Medical and Natural Sciences, 5(5), 13-16. https://www.in-academy.uz/index.php/EJMNS/article/view/10982
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