Articles

BILE ACIDS —A NEW TYPE OF STEROID HORMONES REGULATING NON-SPECIFIC ENERGY EXPENDITURE OF THE ORGANISM

Vol. 5 No. 3 Part 2 (2025): Eurasian Journal of Medical and Natural Sciences 142-144

2025-03-31 Articles CC BY 4.0 Open Access

Authors

  • Ф.А. Бабаджанова Ташкентский Педиатрический Медицинский Институт
  • Ш.A. Аблакулова Ташкентский Педиатрический Медицинский Институт
  • М.Д. Джураева Ташкентский Педиатрический Медицинский Институт

Abstract

Bile acids (BAs) have long been considered exclusively as agents involved in digestion and absorption of fats. However, recent scientific studies have revealed new aspects of their biological activity. Bile acids are now recognized as a novel class of steroid hormones that play a significant role in regulating the body's energy expenditure and influencing metabolic processes, obesity development, and cardiovascular diseases (CVD). This review comprehensively examines the mechanisms of action of bile acids, their impact on energy metabolism, and their potential clinical applications.

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References

Thomas C., Pellicciari R., Pruzanski M. et al. Nature Reviews Drug Discovery. 2008;7(8):678-693.

Kuipers F., Bloks V.W., Groen A.K. Nature Reviews Endocrinology. 2014;10(8):488-498.

Chávez-Talavera O., Tailleux A., Lefebvre P., Staels B. Gastroenterology. 2017;152(7):1679-1694.

Polyzos S.A., Kountouras J., Mantzoros C.S. Metabolism. 2019;92:82-97.

Wahlström A., Sayin S.I., Marschall H.U., Bäckhed F. Cell Metabolism. 2016;24(1):41-50.

Chiang J.Y.L., Ferrell J.M. Gene Expression. 2018;18(2):71-87.

Ridlon J.M., Kang D.J., Hylemon P.B. Current Opinion in Gastroenterology. 2014;30(3):332-338.

Fiorucci S., Distrutti E. Trends in Molecular Medicine. 2015;21(11):702-714.

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    Published

    2025-03-31

    How to Cite

    Бабаджанова , . Ф., Аблакулова , Ш., & Джураева , М. (2025). BILE ACIDS —A NEW TYPE OF STEROID HORMONES REGULATING NON-SPECIFIC ENERGY EXPENDITURE OF THE ORGANISM. Eurasian Journal of Medical and Natural Sciences, 5(3 Part 2), 142-144. https://www.in-academy.uz/index.php/EJMNS/article/view/10922
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