COMPARATIVE ANALYSIS OF CARDIOMETABOLIC PARAMETERS IN PATIENTS WITH CORONARY ARTERY DISEASE WITH AND WITHOUT NAFLD
Keywords:
Coronary heart disease, non-alcoholic fatty liver disease, lipid profile.Abstract
Coronary heart disease (CHD) has been the leading cause of death worldwide for several decades. Non-alcoholic fatty liver disease (NAFLD), the most common liver pathology, is considered a risk factor (RF) for the development of coronary heart disease and a predictor of an unfavourable prognosis. Our study aims to compare cardiometabolic parameters in patients with CHD with and without NAFLD. The study prospectively included 85 patients with CHD, 61 with NAFLD (group I) and 24 without NAFLD (group II). In both groups, a comparative analysis of RF, anthropometric parameters, lipidogram, glycemic profile, and heart structural and geometric parameters according to echocardiography (EchoCG) and coronary calcium parameters was performed. It was found that patients with CHD and NAFLD had statistically significantly higher levels of total cholesterol, very low-density lipoproteins, triglycerides, insulin, structural parameters of the heart and coronary calcium. Thus, the relationship between NAFLD and CHD is two-way, and liver diseases can exacerbate the course of cardiovascular diseases.
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