Articles

TUTQANOQ KASALLIGIDA ISHLATILADIGAN GABAPENTIN DORI MODDASINI TIBBIYOTDA ISHLATILISHI VA KIMYOVIY TAHLIL USULLARINI O‘RGANISH

Vol. 4 No. 6 (Special Issue) (2024): Eurasian Journal of Medical and Natural Sciences 111-112

2024-06-27 Articles CC BY 4.0 Open Access

Authors

  • R.I. Ismoilova Toshkent farmatsevtika instituti, Toshkent shahri, O‘zbekiston Respublikasi
  • Yo.T. Saidkarimova Toshkent farmatsevtika instituti, Toshkent shahri, O‘zbekiston Respublikasi
  • A.B. To’xtayevna Toshkent farmatsevtika instituti, Toshkent shahri, O‘zbekiston Respublikasi

Abstract

Tutqanoq (epilepsiya) kasalligi turli xil xurujlar va xushdan ketishlar bilan nomoyon etuvchi bosh miyaning surunkali kasalligidir. Hozirgi vaqtda  ushbu preparatdan bu kasallikni davolashda keng qo’llanilib kelmoqda qo‘llanilishiga va bu preparat bilan zaharlanish holatlarining kuzatilishiga sabab bo‘lmoqda. Kam uchraydigan asosiy klinik ta’sirlarga quyidagilar kiradi koma, tutqanoq, nafas depressiyasi,  siqilish va ko‘p organli tizimli allergik turdagi reaksiyalarni keltirib chiqaradi. Gabapentin tuzilishi bo‘yicha gamma-aminomoy kislotasining (GAMK) neyrotransmitteri bilan o‘xshash, biroq uning ta’sir mexanizmi, GAMK agonistlari va GAMKning old dori shakllari) boshqa preparatlardan farq qiladi. Gabapentin dori preparatini kimyoviy tahlili to‘liq o‘rganilmagan.  [1,3].

References

G.A.Kim, O. A. Dexanova, I. A. Sokolova “Оптимизация метода ТСХ для обнаружения примесей в противоэпилептическом препарате”

X.Sh Rasulov., Yo.T.Saidkarimova “Gabapentin dori moddasini YuQX usulida tahlilini o‘rganish”

Yo.T. Saidkarimova, F.S. Jalilov // Tutqanoqqa qarshi gabapentin dori preparatining O‘zbekiston farmatsevtika bozorida tutgan o‘rni // 2022 yil 3-son “Farnatsiya” Ilmiy-amaliy jurnali Toshkent-2023 mart oyida chop etildi 19-31 betlar

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    Published

    2024-06-27

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    Vol. 4 No. 6 (Special Issue) (2024): Eurasian Journal of Medical and Natural Sciences

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    How to Cite

    Ismoilova, R., Saidkarimova, Y., & To’xtayevna, A. (2024). TUTQANOQ KASALLIGIDA ISHLATILADIGAN GABAPENTIN DORI MODDASINI TIBBIYOTDA ISHLATILISHI VA KIMYOVIY TAHLIL USULLARINI O‘RGANISH. Eurasian Journal of Medical and Natural Sciences, 4(6 (Special Issue), 111-112. https://www.in-academy.uz/index.php/EJMNS/article/view/10478
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