ACUTE MESENTERIC ISCHEMIA: MODERN APPROACHES TO DIAGNOSIS AND TREATMENT — A SYSTEMATIC REVIEW OF THE LITERATURE
Vol. 6 No. 8 (2026): Eurasian Journal of Academic Research 52-61
Abstract
Acute mesenteric ischemia (OMI) is a severe life-threatening condition that occurs due to a sudden disruption of the intestinal blood supply. The progression of the ischemic process can lead to necrosis of the intestinal wall, peritonitis, sepsis, multiple organ failure and death. Despite improvements in computed tomography diagnostics, endovascular technologies, and intensive care, OMI remains a highly lethal disease. The main forms of the disease are arterial embolism, arterial thrombosis, nonocclusive mesenteric ischemia and mesenteric venous thrombosis.
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References
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. doi:10.1136/bmj.n71.
Bala M, Catena F, Kashuk J, De Simone B, Gomes CA, Weber D, et al. Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery. World J Emerg Surg. 2022;17:54.
Tamme K, Reintam Blaser A, Laisaar KT, et al. Incidence and outcomes of acute mesenteric ischaemia: a systematic review and meta-analysis. BMJ Open. 2022;12:e062846.
Sumbal R, Baig MMA, Sumbal A. Predictors of mortality in acute mesenteric ischemia: a systematic review and meta-analysis. J Surg Res. 2022;275:72-86.
Nuzzo A, et al. Diagnostic accuracy of biomarkers to detect acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis. 2023.
Shi Y, Zhao B, Zhou Y, Chen L, Su H, Gu J. Endovascular revascularization vs open surgical revascularization as the first strategy for arterial acute mesenteric ischemia: a systematic review and meta-analysis. J Vasc Surg. 2024;80(6):1883-1893.e2.
Koelemay MJ, Geelkerken RH, Kärkkäinen J, Leone N, Antoniou GA, de Bruin JL, et al. ESVS 2025 Clinical Practice Guidelines on the Management of Diseases of the Mesenteric and Renal Arteries and Veins. Eur J Vasc Endovasc Surg. 2025;70(2):153-218. doi:10.1016/j.ejvs.2025.06.010.
Zaman MN, Ali W, Dost W, Rasully MQ, Dost R, Niazi J, et al. Endovascular Versus Open Surgical Approaches for Acute Mesenteric Ischemia: A Systematic Review of Outcomes. Cureus. 2025;17(5):e85013. doi:10.7759/cureus.85013.
Reintam Blaser A, et al. Management of acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis. World J Emerg Surg. 2025.
Murphy B, et al. Open and endovascular management of acute mesenteric ischaemia: a systematic review. 2019.
Kärkkäinen JM, Acosta S. Acute mesenteric ischemia: diagnosis and treatment. Best Pract Res Clin Gastroenterol. 2017.
Oldenburg WA, Lau LL, Rodenberg TJ, Edmonds HJ, Burger CD. Acute mesenteric ischemia: a clinical review. Arch Intern Med. 2004;164:1054-1062.
Clair DG, Beach JM. Mesenteric ischemia. N Engl J Med. 2016;374:959-968.
Tilsed JVT, Casamassima A, Kurihara H, Mariani D, Martinez I, Pereira J, et al. ESTES guidelines: acute mesenteric ischaemia. Eur J Trauma Emerg Surg. 2016;42:253-270.
Cudnik MT, Darbha S, Jones J, Macedo J, Stockton SW, Hiestand BC. The diagnosis of acute mesenteric ischemia: a systematic review and meta-analysis. Acad Emerg Med. 2013;20:1087-1100.
Menke J. Diagnostic accuracy of multidetector CT in acute mesenteric ischemia: systematic review and meta-analysis. Radiology. 2010;256:93-101.
Bala M, Kashuk J, Moore EE, Kluger Y, Biffl W, Gomes CA, et al. Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery. World J Emerg Surg. 2017;12:38.
Nuzzo A, et al. Serological markers for human intestinal ischemia: systematic review. Best Pract Res Clin Gastroenterol. 2017.
Oldenburg WA, et al. Acute mesenteric ischemia: a clinical review. Arch Intern Med. 2004;164:1054-1062.
Kozuch PL, Brandt LJ. Review article: diagnosis and management of mesenteric ischemia with an emphasis on pharmacotherapy. Aliment Pharmacol Ther. 2005;21:603-616.
Clair DG, Beach JM. Mesenteric ischemia. N Engl J Med. 2016;374:959-968.
Kärkkäinen JM, Acosta S. Acute mesenteric ischemia: diagnosis and treatment. Best Pract Res Clin Gastroenterol. 2017.
Acosta S. Epidemiology of mesenteric vascular disease: clinical implications. Semin Vasc Surg. 2010.
Björck M, Koelemay M, Acosta S, Bastos Gonçalves F, Kölbel T, Kolkman JJ, et al. Editor's Choice — Management of the diseases of mesenteric arteries and veins: clinical practice guidelines of the European Society of Vascular Surgery. Eur J Vasc Endovasc Surg. 2017.
Page MJ, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ. 2021;372:n160.
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