GLYCYRRHETINIC ACID IN MODERN DRUG DISCOVERY AND CANCER THERAPY
Keywords:
Network Pharmacology and Modern Drug Discovery. The expert consensus article highlights the growing importance of network pharmacology in TCM researchAbstract
Glycyrrhetinic acid (GA), a bioactive triterpenoid derived from licorice, has attracted considerable attention due to its anti-inflammatory, antioxidant, and anticancer properties. Recent advances in network pharmacology, molecular biology, and medicinal chemistry have enabled researchers to better understand the complex mechanisms of GA and its derivatives. This review summarizes the major findings from three representative publications and discusses the role of network pharmacology in traditional medicine drug development, the antitumor mechanisms of glycyrrhetinic acid, and the therapeutic potential of GA derivatives in cancer treatment.
References
General expert consensus on the application of network pharmacology in the research and development of new traditional. Chinese medicine drugs. Shao Lia,*, Wei Xiaob;
Anti cancer activity of the glycyrrhetinic acid derivatives with an inhibitory inflammatory microenvironment. Jianrong Liu, Tianbo Wu, Wei Li, Quanyi Zhao, Dian He;
The antitumor mechanism of glycyrrhetinic acid and its applications in cancer treatment Deru Zhang, Yuxin Liu, Mengke Wang, Hanning Lyu, Yang Sun.
Shao L., Xia W. General expert consensus on the application of network pharmacology in the research and development of new traditional Chinese medicine drugs.
Liu J., Wu T., Li W., Zhao Q., He D. Anti-cancer activity of the glycyrrhetinic acid derivatives with an inhibitory inflammatory microenvironment.
Zhang D., Liu Y., Wang M., Lyu H., Sun Y. The antitumor mechanism of glycyrrhetinic acid and its applications in cancer treatment.
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