SIKORIY O‘SIMLIGINING GEPATOPROTEKTORLIK XUSUSIYATLARI
Keywords:
sikoriy, Cichorium intybus L., gepatoprotektor, jigar, flavonoidlar, inulin, antioksidant, detoksikatsiya, fitoterapiya.Abstract
Mazkur maqolada sikoriy o‘simligi — Cichorium intybus L. ning gepatoprotektorlik xususiyatlari, kimyoviy tarkibi, biologik faol moddalari hamda jigar faoliyatiga ta’siri tahlil qilinadi. Sikoriy qadimdan xalq tabobatida jigar, ovqat hazm qilish tizimi va modda almashinuvi bilan bog‘liq holatlarda qo‘llanib kelinadi. Uning tarkibida inulin, flavonoidlar, fenol birikmalari, organik kislotalar, seskviterpen laktonlar, vitaminlar va antioksidant moddalar mavjud bo‘lib, ular jigar hujayralarini oksidlovchi stress, toksik shikastlanish va yallig‘lanish jarayonlaridan himoya qilishda muhim ahamiyatga ega. Maqolada sikoriyning jigarni himoya qilish mexanizmlari, detoksikatsiya jarayonlariga ta’siri, gepatotsitlar regeneratsiyasini qo‘llab-quvvatlashi hamda farmatsevtik va xalq tabobatidagi qo‘llanilish imkoniyatlari yoritilgan.
References
Pratibha, S., & Gupta, M. (2017). Hepatoprotective effect of Cichorium intybus on liver damage induced by carbon tetrachloride in rats. Pharmacognosy Journal, 9(3), 298–305.
Ali, B. H., & Blunden, G. (2003). Pharmacological and toxicological properties of Cichorium intybus L.: A review. Phytotherapy Research, 17(7), 489–498.
Srinivasan, M., & Sudhakar, M. (2015). Hepatoprotective and antioxidant effects of Cichorium intybus L. against drug-induced liver damage in albino rats. International Journal of Pharmacology, 11(4), 283–291.
Santos, A. M., & Rodrigues, M. A. (2019). Medicinal properties and uses of Cichorium intybus in traditional medicine. Journal of Medicinal Plants Research, 13(5), 128–135.
Kumar, V., & Sood, S. (2014). The potential of Cichorium intybus in hepatoprotective treatment. Asian Journal of Pharmaceutical and Clinical Research, 7(3), 1–5.
Hussain, S. J., & Sadiq, M. (2021). A review on Cichorium intybus and its potential applications in hepatology. Journal of Herbal Medicine, 30, 100497.
Chaudhary, N. A., & Khan, M. (2016). Chicory (Cichorium intybus): A natural remedy for liver protection. Biological and Pharmaceutical Bulletin, 39(4), 521–527.
Li, G. Y., Gao, H. Y., Huang, J., Lu, J., Gu, J. K., & Wang, J. H. (2014). Hepatoprotective effect of Cichorium intybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats. World Journal of Gastroenterology, 20(16), 4753–4760.
Street, R. A., Sidana, J., & Prinsloo, G. (2013). Cichorium intybus: Traditional uses, phytochemistry, pharmacology, and toxicology. Evidence-Based Complementary and Alternative Medicine, 2013, 579319.
Maleki, E., et al. (2023). The effects of chicory supplementation on liver enzymes and metabolic parameters in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis. Phytotherapy Research.
Downloads
Published
Issue
Section
How to Cite
