ISITMA ETIOLOGIYASI, KLINIK KECHISHI VA PATOGENEZI
Keywords:
isitma, etiologiya, patogenez, termoregulyatsiya, gipotalamus, prostaglandin E2, pirogen, infeksiya, patologik anatomiya, yallig‘lanish, klinik kechish.Abstract
Ushbu maqolada isitmaning (pyreksiyaning) etiologiyasi, klinik kechishi va patogeneziga oid dolzarb jihatlar patologik anatomiya fani doirasida keng yoritilgan. Isitma organizmning yallig‘lanish, infeksion yoki toksik omillarga javoban rivojlanadigan kompleks himoya va moslashuv reaksiyasi bo‘lib, uning asosida termoregulyatsiya markazining o‘zgarishi yotadi. Maqolada isitmaga olib keluvchi asosiy sabablar sifatida infeksion agentlar (bakteriyalar, viruslar, parazitlar), immun reaksiyalar, onkologik jarayonlar, dori vositalari va metabolik buzilishlar ko‘rsatilgan. Shuningdek, isitmaning rivojlanish mexanizmlari (pirogenlarning roli, prostaglandin E2 ishtiroki) ilmiy asosda yoritilgan. Klinik belgilari bosqichma-bosqich tahlil qilinib, isitmaning turlari – doimiy, to‘lqinsimon, hektik, intermittent va atipik isitmalar ajratib ko‘rsatilgan. Maqolada isitmaning patologik anatomik o‘zgarishlari, ya’ni yurak, jigar, buyrak, asab tizimi va qon aylanish tizimida yuzaga keluvchi morfologik o‘zgarishlar keng bayon etilgan. Ushbu ilmiy ish tibbiyot sohasi mutaxassislari, talabalar va tadqiqotchilar uchun nazariy hamda amaliy jihatdan foydali manba hisoblanadi.
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