MODELLASHTIRILGAN HAYVONLARDA INSULIN REZISTENLIGI KELIB CHIQISHINING FIZIOLOGIK XUSUSIYATLARI
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insulin rezistenligi, laboratoriya hayvonlari, fiziologik mexanizmlar, yallig‘lanish, glyukoza utilizatsiyasi, lipogenez, adiponektin, oksidlovchi stress.Abstrak
Ushbu maqolada laboratoriya sharoitida insulin rezistenligi (IR) modellashtirilgan hayvonlarda kuzatiladigan asosiy fiziologik mexanizmlar batafsil tahlil qilinadi. Skelet mushaklari, jigar, yog‘ to‘qimasi, pankreas, gipotalamus-gipofizar-adrenal tizim hamda immun-endokrin tizimidagi o‘zgarishlarning IR rivojlanishidagi patofiziologik ahamiyati ko‘rib chiqiladi va ilmiy tadqiqotlar asosida yoritiladi.
Iqtiboslar
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