MODELLASHTIRILGAN HAYVONLARDA INSULIN REZISTENLIGI KELIB CHIQISHINING FIZIOLOGIK XUSUSIYATLARI
Jild 4 son 25 (2025): Innovative research in the modern world: theory and practice 140-142
Annotatsiya
Ushbu maqolada laboratoriya sharoitida insulin rezistenligi (IR) modellashtirilgan hayvonlarda kuzatiladigan asosiy fiziologik mexanizmlar batafsil tahlil qilinadi. Skelet mushaklari, jigar, yog‘ to‘qimasi, pankreas, gipotalamus-gipofizar-adrenal tizim hamda immun-endokrin tizimidagi o‘zgarishlarning IR rivojlanishidagi patofiziologik ahamiyati ko‘rib chiqiladi va ilmiy tadqiqotlar asosida yoritiladi.
Kalit soʻzlar:
Iqtiboslar
Samuel, V. T., & Shulman, G. I. (2016). The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux. The Journal of Clinical Investigation, 126(1), 12–22.
Petersen, M. C., & Shulman, G. I. (2018). Mechanisms of insulin action and insulin resistance. Physiological Reviews, 98(4), 2133–2223.
Czech, M. P. (2017). Insulin action and resistance in obesity and type 2 diabetes. Nature Medicine, 23(7), 804–814.
Reaven, G. M. (2005). Insulin resistance, cardiovascular disease, and the metabolic syndrome. Diabetes Care, 28(4), 895–900.
Hotamisligil, G. S. (2017). Inflammation, metaflammation and immunometabolic disorders. Nature, 542(7640), 177–185.
Oʻquvchilar geografiyasi
Nashr qilingan
Son
Boʻlim
Iqtibos keltirish tartibi
