IN VITRO ANTIOXIDANT ACTIVITY EVALUATION OF SNEDDS-BASED FORMULATIONS USING DPPH ASSAY
DOI:
https://doi.org/10.5281/zenodo.19565199Ключевые слова:
SNEDDS; antioxidant activity; DPPH assay; plant extracts; curcumin; grape seed extract; Melissa officinalis; controlled release; nanoemulsion; bioavailability enhancement; free radical scavenging.Аннотация
This study investigates the in vitro antioxidant activity of plant-derived extracts and self-nanoemulsifying drug delivery systems (SNEDDS)-based formulations using the DPPH assay. Oxidative stress is a key factor in the pathogenesis of various diseases, which has led to increased interest in antioxidant-rich formulations. However, many plant-derived bioactive compounds suffer from poor solubility and limited bioavailability, restricting their therapeutic potential.
Библиографические ссылки
Brand-Williams, W., Cuvelier, M.E. & Berset, C. (1995). Use of a free radical method to evaluate antioxidant activity. LWT - Food Science and Technology, 28, 25–30.
Rice-Evans, C., Miller, N.J. & Paganga, G. (1997). Antioxidant properties of phenolic compounds. Trends in Plant Science, 2, 152–159.
Shakeel, F. et al. (2008). Self-nanoemulsifying drug delivery system: a review. AAPS PharmSciTech, 9, 1236–1243.
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