IN VITRO ANTIOXIDANT ACTIVITY EVALUATION OF SNEDDS-BASED FORMULATIONS USING DPPH ASSAY
Keywords:
SNEDDS; antioxidant activity; DPPH assay; plant extracts; curcumin; grape seed extract; Melissa officinalis; controlled release; nanoemulsion; bioavailability enhancement; free radical scavenging.Abstract
This study investigates the in vitro antioxidant activity of plant-derived extracts and self-nanoemulsifying drug delivery systems (SNEDDS)-based formulations using the DPPH assay. Oxidative stress is a key factor in the pathogenesis of various diseases, which has led to increased interest in antioxidant-rich formulations. However, many plant-derived bioactive compounds suffer from poor solubility and limited bioavailability, restricting their therapeutic potential.
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