CARDIOVASCULAR ADAPTATIONS AND DISEASE TRAJECTORY OF DIABETIC CARDIOMYOPATHY IN TYPE 2 DIABETES UNDER PROLONGED HEAT EXPOSURE: TOWARD PERSONALIZED CLIMATE-SENSITIVE MANAGEMENT STRATEGIES

Abstract

This reformulated title underscores the integrated pathophysiological mechanisms and evolving clinical patterns of diabetic cardiomyopathy (DCM) in individuals with type 2 diabetes mellitus (T2DM) inhabiting hot climatic environments. The review delves into heat-related metabolic stressors, cardiovascular maladaptations, and proposes patient-centered, climate-conscious therapeutic models tailored for sustained cardiometabolic resilience.