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ENDOMETRIAL RETSEPTIVLIK BUZILIGAN HOLATLARDA TROMBOTSITLARGA BOY PLASMA SAMARADORLIGINI OSHIRISH: ZAMONAVIY REGENERATIV VA IMMUNOMODULYATOR STRETEGIYALAR

Jild 4 son 21 (2025): Science and technology in the modern world 6-8

DOI: 10.5281/zenodo.16759428 2025-08-06 Maqolalar Open Access

Mualliflar

  • Suraya Yuldasheva Toshkent Pediatriya Tibbiyot instituti Akusherlik, ginekologiya va o’smir qizlar ginekologiyasi dotsenti, tibbiyot fanlari doktori.
  • Nilufar Abdullayeva Toshkent Pediatriya Tibbiyot Instituti, Farmakologiya, normal va patalogik fiziologiya kafedrasi assestenti

Annotatsiya

Endometrial retseptivlik – bu bachadon shilliq qavatining embrionni qabul qilish va muvaffaqiyatli implantatsiya qilishga tayyor holatidir. Ushbu holatning buzilishi bepushtlikning asosiy sabablaridan biri hisoblanadi, ayniqsa, endometrioz, surunkali endometrit yoki yupqa endometriy fonida kuzatiladi. Retseptivlik buzilganda, hatto sog‘lom va sifatli embrion ham endometriyga yopishmaydi.

Kalit soʻzlar:

Iqtiboslar

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Obidniak D., Gzgzyan A., Niauri D., et al.Randomized controlled trial evaluating efficacy of autologous platelet-rich plasma therapy for patients with recurrent implantation failure.Human Reproduction, 2023; 38(S1): dead093.

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Chang Y., Li J., Chen Y., et al.Autologous platelet-rich plasma promotes endometrial growth and improves pregnancy outcome during IVF.Int J Clin Exp Med, 2015; 8(1): 1286–1290.

Jang H., Kim H., Lee J.H., Kim J.Molecular signature of PRP-induced regeneration in endometrial tissue.J Assist Reprod Genet, 2021; 38(5): 1061–1070.

Salamonsen L.A., Dimitriadis E., Evans J.Dynamic changes in the endometrial microenvironment during the menstrual cycle.Reproduction, 2016; 152(6): R127–R137.

Wu X., Wang Y., Wei L., Liu L.TGF-β1-induced collagen synthesis in endometrial stromal cells through Smad2/3 and CTGF pathways.J Cell Physiol, 2023; 238(1): 89–97.

Nashr qilingan

2025-08-06

Iqtibos keltirish tartibi

Yuldasheva , S. ., & Abdullayeva , N. . (2025). ENDOMETRIAL RETSEPTIVLIK BUZILIGAN HOLATLARDA TROMBOTSITLARGA BOY PLASMA SAMARADORLIGINI OSHIRISH: ZAMONAVIY REGENERATIV VA IMMUNOMODULYATOR STRETEGIYALAR. Zamonaviy Dunyoda Ilm-Fan Va Texnologiya, 4(21), 6-8. https://doi.org/10.5281/zenodo.16759428
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