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WAYS TO PREVENT SIDE EFFECTS OF NONSTEROIDAL DRUGS

Jild 4 son 2 (2025): «Zamonaviy dunyoda ilm-fan va texnologiya» 44-46

DOI: 10.5281/zenodo.14752771 2025-01-27 Maqolalar Open Access

Mualliflar

  • Islombek Sobirjonov Andijan State Medical Institute

Annotatsiya

Adverse effects of medications, particularly those affecting the kidneys and cardiovascular system, represent a significant global medical concern. Non-steroidal anti-inflammatory drugs (NSAIDs) are among the primary contributors to these complications, as they are one of the most widely used drug classes. The pharmacological action of NSAIDs involves inhibiting the synthesis of vasodilatory renal prostaglandins by deactivating the cyclooxygenase enzyme. This inhibition can result in vasomotor acute kidney injury, acute tubulointerstitial nephritis, chronic kidney disease, and other renal complications.

Kalit soʻzlar:

Iqtiboslar

Musu M et al. Acute nephrotoxіcіty of NSAІD from the fetus to the adult. Eur Rev Med Pharmacol Scі 2011; 15 (12): 1461–72.

Davіs A, Regіstrar G. The dangers of NSAІDs: look both ways. Br J Gen Pract 2016; 66 (645): 172–3. DOІ: 10.3399/bjgp16X684433

Paі A. Keepіng kіdneys safe: the pharmacіst`s role іn NSAІD avoіdance іn hіgh-rіsk patіents. Pharmacy Today 2014; 20 (12): 54–64.

Hörl W et al. Nonsteroіdal Antі-Іnflammatory Drugs and the Kіdney. Pharmaceutіcals (Basel) 2010; 3 (7): 2291–321.

Nashr qilingan

2025-01-27

Iqtibos keltirish tartibi

Sobirjonov , I. . (2025). WAYS TO PREVENT SIDE EFFECTS OF NONSTEROIDAL DRUGS. Zamonaviy Dunyoda Ilm-Fan Va Texnologiya, 4(2), 44-46. https://doi.org/10.5281/zenodo.14752771
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