DIAGNOSTIC VALUE OF CA-125, HE-4 AND RISK OF OVARIAN MALIGNANCY ALGORITHM IN DIAGNOSING OF OVARIAN CANCER IN PRE- AND POSTMENOPAUSAL WOMEN

Abstract

Ovarian cancer is responsible for the most deaths in the  gynecological  sphere. The advancements in science and  modern  diagnostic methods  made possible the  thorough  investigation of this organ but there are still unsolved questions. The aim of this study is to estimate the predictive value of measuring CA-125, HE-4, and Risk of Malignancy Algorithm (ROMA) in the diagnosis of ovarian malignant tumors in pre- and postmenopausal women at the stage of preoperative examination.