YURAK YETISHMOVCHILIGI BO'LGAN BEMORLARDA DIURETIKLARNI UZOQ MUDDAT QO'LLASH FONIDA MUSHAK GIPERKINEZLARINING RIVOJLANISH MEXANIZMLARI
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Abstract:
Yurak yetishmovchiligi bo‘lgan bemorlarni davolashda diuretik preparatlar asosiy dori vositalaridan biri hisoblanadi. Ularni uzoq muddat qo‘llash suv-elektrolit muvozanatining buzilishiga olib kelib, neyromushak qo‘zg‘aluvchanligining ortishi bilan namoyon bo‘ladigan turli xil mushak giperkinezlariga sabab bo‘lishi mumkin. Ushbu tezisda diuretiklar fonida rivojlanadigan gipokaliemiya, gipomagnezemiya va metabolik alkalozning patofiziologik ahamiyati, shuningdek, ularning markaziy va periferik asab tizimiga ta’sir mexanizmlari tahlil qilinadi. Mushak giperkinezlarining klinik ahamiyati va ularni erta aniqlashning profilaktik ahamiyati yoritilgan.
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