THE EFFECT OF HUMORAL IMMUNITY ON URIC ACID CRYSTALS
Abstract
In 2023, approximately 305 million people worldwide were affected by hyperuricemia, a metabolic condition characterized by elevated levels of uric acid in the blood. Despite its high prevalence, only about 10–36% of individuals with hyperuricemia eventually develop gout, indicating that additional pathogenic factors contribute to disease progression. Gout is an inflammatory arthritis caused by the deposition of monosodium urate crystals in joint tissues, leading to recurrent episodes of severe pain and inflammation.
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