BACHADON BO’YNI SARATONI: ERTA ANIQLASH DAVOLASH VA PROFILAKTIKA
DOI:
https://doi.org/10.5281/zenodo.20525536Keywords:
Bachadon bo‘yni saratoni, HPV, E6, E7, p53, Rb, apoptoz, hujayra sikli, Warburg effekti, kimyoterapiya, radioterapiya, profilaktika, skrining.Abstract
Bachadon bo‘yni saratoni (BBs) ayollar orasida keng tarqalgan onkologik kasallik bo‘lib, uning asosiy etiologik omili yuqori xavfli inson papilloma virusi (HPV) hisoblanadi. Kasallik rivojlanishida virusning E6 va E7 onkoproteinlari orqali p53 va Rb tumor supressor genlarining inaktivatsiyasi muhim rol o‘ynaydi. Bu hujayra siklining buzilishi, DNK reparatsiyasining to‘xtashi, apoptozning yo‘qolishi va metabolik qayta dasturlanish (Warburg effekti) bilan kechadi. Maqolada kasallikning epidemiologiyasi, patogenezi, klinik belgilari, diagnostikasi, zamonaviy davolash usullari va profilaktika choralari keng yoritilgan.References
World Health Organization (WHO). Cervical Cancer Strategy 2020–2030.
FIGO Guidelines.
NCCN Oncology Guidelines.
Novak’s Gynecology.
Williams Gynecology.
Robbins & Cotran Pathologic Basis of Disease.
International Agency for Research on Cancer (IARC).
Ministry of Health Clinical Protocols.
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2026-06-03
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This work is licensed under a Creative Commons Attribution 4.0 International License.
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Mansurova, K. (2026). BACHADON BO’YNI SARATONI: ERTA ANIQLASH DAVOLASH VA PROFILAKTIKA. Pedagogy and Psychology in the Modern World, 5(13), 11-14. https://doi.org/10.5281/zenodo.20525536
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