THE IMPORTANCE OF IMMUNODIAGNOSTICS IN THE DIAGNOSIS OF LIVER DISEASES IN MODERN MEDICINE

Аннотация

Liver diseases are characterized by etiological diversity and diagnostic complexity. Viral hepatitis, autoimmune hepatitis, cholestatic disorders, drug-induced liver injury, and metabolic liver diseases may present with similar clinical and biochemical manifestations, while their pathogenetic mechanisms differ substantially [1]. One of the main challenges in clinical practice is that hepatic pathology often develops gradually and may remain asymptomatic for a long time. As a result, many patients are diagnosed at advanced stages, when structural and functional liver damage is already pronounced. This significantly reduces the effectiveness of treatment and worsens long-term prognosis [1]. In such conditions, laboratory methods capable of identifying disease-specific immune mechanisms acquire particular diagnostic importance [2].