BIOLOGICAL SIGNIFICANCE OF SYNTHETIC DRUGS AND INFUSION SOLUTIONS IN THE DEVELOPMENT OF NOVEL HEPATOPROTECTIVE COMBINATIONS

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Выпуск: Том 6 № 1 : Евразийский журнал медицинских и естественных наук
Раздел: Статьи
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Chief Specialist of the Primary Expertise Department, State Institution “Center of Good Practices”, Agency for the Development of the Pharmaceutical Industry under the Ministry of Health of the Republic of Uzbekistan
amirhonumiridinov@gmail.com
Tashkent Pharmaceutical Institute
toshtemirovac@gmail.com

Аннотация:

The increasing incidence of liver pathologies has intensified the need for the development of new-generation hepatoprotective agents in modern pharmacology. This article analyzes the biological significance of hepatoprotective combinations developed on the basis of synthetic drug substances and infusion solutions. The effects of a combination consisting of monoammonium glycyrrhizinate, glycine, and L-cysteine hydrochloride on hepatocyte stability, antioxidant system activity, and endogenous detoxification mechanisms are examined. The biological synergy of the components is scientifically substantiated as a factor that enhances the effectiveness of complex therapy for liver and biliary system diseases.

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Как цитировать:

Umirdinova, V. ., & Toshtemirova, C. (2026). BIOLOGICAL SIGNIFICANCE OF SYNTHETIC DRUGS AND INFUSION SOLUTIONS IN THE DEVELOPMENT OF NOVEL HEPATOPROTECTIVE COMBINATIONS. Евразийский журнал медицинских и естественных наук, 6(1), 98–101. извлечено от https://www.in-academy.uz/index.php/EJMNS/article/view/72110

Библиографические ссылки:

Ivashkin V.T., Drapkina O.M. Pathogenetic principles of hepatoprotective therapy. Terapevticheskii Arkhiv, 2020.

European Association for the Study of the Liver (EASL). Clinical Practice Guidelines on liver and biliary diseases. Journal of Hepatology, 2018.

Gao Y., Wang Z. Glycyrrhizic acid derivatives in liver disease treatment. Pharmacological Research, 2021.

Lu S.C., Mato J.M. Glutathione metabolism and liver protection. Hepatology, 2019.

Katzung B.G. Basic and Clinical Pharmacology. McGraw-Hill, 2020.

Тоштемирова Ч.Т., Мадатова Н.Ф. Маркетинговый анализ противодиарейных лекарственных средств // Universum: медицина и фармакология.- 2024.- 4(109). –С.46-53(ISSN: 2311-6129; Ulrich’s Periodicals Directory).

Тоштемирова Ч.Т., Дусчанова Г.М., Нормахаматов Н.С. Структурные особенности надземных и подземных органов лекарственного растения Gentiana Olivieri Griseb.. произрастающего в условиях Джизака// Фармацевтический журнал.- №4.-2024.-C.5-15

Тоштемирова Ч.Т.., Нормахаматов Н.С. Ўзбекистонда ўсадиган доривор GentianOlivieri Griseb.нинг элементлар таркибини ўрганиш // Eurasian journal of medical and natural sciences.-2024.-Vol.4.-Issue 10,-P.87-90(ISSN 2181-278X; ResearchBib=7,924).