WAYS TO INCREASE THE EFFECTIVENESS OF COMBINATION THERAPY FOR PULMONARY TUBERCULOSIS USING DRUG SENSITIVITY TESTING OF MBT ON SURGICAL SAMPLES IN PATIENTS WITH NON-BACTERIAL PULMONARY TUBERCULOSIS

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Issue: Vol. 6 No. 1 : Eurasian Journal of Academic Research
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Бухарский областной центр фтизиатрии и пульмонологии, фтизиохирург
info@in-academy.uz

Abstract:

Non-bacillary pulmonary tuberculosis is a complex clinical and diagnostic form of the disease, in which standard microbiological verification of the pathogen is impossible. In such circumstances, the use of surgical specimens to determine the drug susceptibility of Mycobacterium tuberculosis (MBT) is particularly important, allowing for the optimization of anti-tuberculosis treatment regimens. This article examines ways to improve the effectiveness of combination therapy for pulmonary tuberculosis in patients without bacillary excretion, taking into account the results of MBT drug susceptibility testing obtained from surgical specimens. It analyzes the possibilities of individualizing chemotherapy, increasing the clinical efficacy of treatment, and reducing the risk of drug resistance and relapse rates.

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How to Cite:

Холбоев , Э. . (2026). WAYS TO INCREASE THE EFFECTIVENESS OF COMBINATION THERAPY FOR PULMONARY TUBERCULOSIS USING DRUG SENSITIVITY TESTING OF MBT ON SURGICAL SAMPLES IN PATIENTS WITH NON-BACTERIAL PULMONARY TUBERCULOSIS. Eurasian Journal of Academic Research, 6(1), 45–53. Retrieved from https://www.in-academy.uz/index.php/ejar/article/view/71170

References:

World Health Organization. Global tuberculosis report. Geneva: WHO; 2023.

Фтизиатрия: национальное руководство / под ред. М.И. Перельмана. Москва: ГЭОТАР-Медиа; 2022.

Мишин В.Ю., Эргашев Ш.А., Сотникова Т.Н. Современные подходы к лечению туберкулеза легких без бактериовыделения. Туберкулез и болезни легких. 2021;99(4):5–12.

Каминский Г.Д., Мордык А.В. Хирургическое лечение туберкулеза легких: показания и результаты. Хирургия. Журнал им. Н.И. Пирогова. 2020;(6):45–51.

Zumla A., Raviglione M., Hafner R., von Reyn C.F. Tuberculosis. New England Journal of Medicine. 2013;368(8):745–755.

Mitchison D.A., Davies G.R. The chemotherapy of tuberculosis: past, present and future. International Journal of Tuberculosis and Lung Disease. 2012;16(6):724–732.

Мордык А.В., Кононенко И.В., Чубукова О.А. Лекарственная устойчивость микобактерий туберкулеза и пути ее преодоления. Клиническая медицина. 2019;97(3):204–209.

Lawn S.D., Zumla A.I. Tuberculosis. Lancet. 2011;378(9785):57–72.

Турсунов Д.А., Абдуллаев Р.А. Морфологические особенности туберкулеза легких при различных клинических формах. Архив патологии. 2020;82(2):38–44.

Falzon D., Schünemann H.J., Harausz E., et al. World Health Organization treatment guidelines for drug-resistant tuberculosis. European Respiratory Journal. 2017;49(3):1602308