EARLY NEONATAL COMPLICATIONS IN CHOLESTATIC HEPATOSIS OF PREGNANCY (CLINICAL CASES FROM PRACTICE)

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Abstract:

Cholestatic hepatosis of pregnancy (CHP) is the most common liver pathology during pregnancy. This disease has a complex multifactorial pathogenesis. The main clinical manifestation is skin itching without skin rashes. CHP leads to the development of pregnancy complications such as premature birth, severe respiratory distress syndrome, often accompanied by meconium staining of amniotic fluid. These complications of pregnancy and the perinatal period are accompanied by high perinatal morbidity and mortality. In this article, we describe two cases of pregnancy complicated by intrahepatic cholestasis, with early neonatal death of newborns in two perinatal centers in Tashkent. The conducted anamnestic, clinical and pathomorphological study, as well as the identification of possible predictors of perinatal death of newborns from mothers with cholestatic hepatosis of pregnancy will help prevent negative outcomes in the future.

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How to Cite:

Топхара , Е., Абдурахманова, Б., Аликулова, Ш., Ниязметов, Р., & Матякубов, Б. (2024). EARLY NEONATAL COMPLICATIONS IN CHOLESTATIC HEPATOSIS OF PREGNANCY (CLINICAL CASES FROM PRACTICE). Eurasian Journal of Academic Research, 4(10), 117–123. Retrieved from https://www.in-academy.uz/index.php/ejar/article/view/38646

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